This module builds on TM2203 and explores the principles that determine the chemistry of the p, d and f transition series. The chemistry of the nucleus is explored and the applications of radioactivity in diagnostics and radiotherapy are presented. The structure and electronic and magnetic properties of solid state materials
A selection of the following topics or part thereof will be covered each year:
Main Group Chemistry:
A selection of the p-block elements/groups will be chosen each session :
- Group 13: Trends in chemistry of B, Al, Ga, In and Tl
- Group14: Trends in the chemistry of C Si Ge Sn Pb including silicates, silicones, zeolites,
- Group 15. Comparison of nitrogen with phosphorus to illustrate the variety of oxidation states, pi bonding and expanded valancy for phosphorus. Phosphates and polyphosphates. Oxides of nitrogen.
- Group 16 Oxygen and sulphur chemistry including peroxides, superoxides and peroxoacids.
d and f block Chemistry
Periodic trends in the transition series d block and f block chemistry. Electron density, oxidation and reduction, typical reactions of the aqua ions. Comparison between d block and f block. Typical reactions. NMR activity of inorganic nuclei and inorganic NMR spectroscopy. USE of NMR in diagnostics.
Radioceuticals
Natural and induced radioactivity, stability of the nucleus, binding energy and decay profiles and half life. Impact of radiation on biological systems, Dose calculations. Uses of radiation in the treatment of disease. Imaging agents used in diagnostics, radioceuticals used as therapeutic agents
Design of metal complexes for diagnostics and therapy.
Fundamental aspects of Solid State Materials
Structure: Review main structures crystal lattices, unit cells, close packed and non-close packed. Introduction to more complex structures such as perovskite and spinel.
Reactions: Solid state reactions, preparative methods, factors affecting rates, , melt reactions.
Metals. Bonding models; structure of metals; alloys (the solid solution and the alloy compounds), nanometal particles. Magnetic properties.
Synthesis of Inorganic solids
Solid state reactions: Solid solutions, phase diagrams, direct reactions, precursor methods, Preparation from solutions, sols, gels, and melts.
Electronic Conduction
Introduction to band theory and how it explains electronic structure and electronic conduction in solids. Insulators, semiconductors, and metallic conductors. Electronic conduction properties and trends of the group 14 elements. Solid state inorganic compounds in medicine.
Inorganic chemistry in the laboratory, experimental techniques 2
Experimental techniques including purification techniques, elemental analysis, thermogravimetric analysis, vibrational spectroscopy, electronic absorption spectroscopy .
Practical Inorganic Chemistry
Five three hour laboratory sessions will be completed.
Laboratory work is sourced from the School of Chemical and Pharmaceutical Sciences Laboratory manual.
The module is delivered through a series of lectures (20 hours), tutorials (4 hours), laboratory practical classes (15 hours) and self-directed study (61 hours).
| Module Content & Assessment | |
|---|---|
| Assessment Breakdown | % |
| Formal Examination | 60 |
| Other Assessment(s) | 40 |