Module Overview

Transfusion Science and Transplantation

This module will provide an advanced state-of-the-art overview of current theoretical and applied transfusion science practices, with emphasis on emerging clinical concerns and new technical approaches. The purpose of this module is to update students on current best practice in blood transfusion and transplantation science in Ireland. It will deepen knowledge in the area of blood group systems and transfusion issues in different patient cohorts. It will also review the medical uses of red cells and other blood products. It will provide a review of the theory and practice of tissue banking and organ transplantation. The current best-practice in relation to organ transplantation and tissue banking from a laboratory perspective will be covered.

Module Code

BIOL 9233

ECTS Credits

10

*Curricular information is subject to change

The EU Directive legislation as applied to blood banks and other establishments;

-  Haemovigilance, its impact on the laboratory. The role of the National Haemovigilance office;

-  Accreditation: its impact and benefits in relation to the blood transfusion laboratory and the patient;

-  Blood and blood component preparation. The appropriate use of blood and blood products, including conservation strategies to reduce exposure to risk;

-  Current and emerging risks associated with transfusion, both serological and non-serological. - Transfusion transmitted infection and attempts to control it;

-  Specialised cases: transfusion of neonates; transfusion in emergency and trauma situations; massive transfusions;

-  The immune response to transfusion. Blood group antigens, their structure, function and genetics;

-  Red cell blood products, their preparation, storage and use and the storage lesion in red cells.

Overview of current technology and practice in Tissue Banking and Transplantation.

Outline of the legal and regulatory framework surrounding tissue banking in Ireland.

-Current best practice in organ procurement and transplantation co-ordination

Indicative Syllabus

The EU Directive legislation as applied to blood banks and other establishments;Haemovigilance, its impact on the laboratory. The role of the National Haemovigilance office;Accreditation: its impact and benefits in relation to the blood transfusion laboratory and the patient;Blood and blood component preparation. The appropriate use of blood and blood products, including conservation strategies to reduce exposure to risk;Current and emerging risks associated with transfusion, both serological and non-serological. -Transfusion transmitted infection and attempts to control it;Specialised cases: transfusion of neonates; transfusion in emergency and trauma situations; massive transfusions;The immune response to transfusion. Blood group antigens, their structure, function and genetics;Red cell blood products, their preparation, storage and use and the storage lesion in red cells.Overview of current technology and practice in Tissue Banking and Transplantation.Outline of the legal and regulatory framework surrounding tissue banking in Ireland.

Teaching will be carried out in class by TU DUBLIN lecturing staff, external experts and peer to peer in the form of presentation on current topics in transfusion / transplantation science. The will also be self-directed learning as part of the assessment process.

Module Content & Assessment
Assessment Breakdown %
Formal Examination70
Other Assessment(s)30